Ibrutinib (140mg) capsules


30 Capsules in 1 Bottle

International NameIbrunat Capsule

MANUFACTURER: Natco Pharma Ltd
SALT COMPOSITION: Ibrutinib (140mg) capsules
FORM: Capsule
PACKAGING: 30 capsules in a bottle


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Ibrunat Capsule is used in the treatment of mantle-cell lymphoma and blood cancer (chronic lymphocytic leukemia). It is also used in chronic lymphocytic leukaemia who have received at least one prior therapy.

Ibrunat Capsule is taken in a dose as advised by the doctor. The duration of treatment varies on the basis of your response to treatment. Your doctor may get regular blood tests to check number of blood cells during treatment with this medicine. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections.  It may cause headache, diarrhea, and nausea as its side effects.


  • Mantle-cell lymphoma
  • Blood cancer (Chronic lymphocytic leukemia)


Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ibrunat

  • Headache
  • Joint pain
  • Fever
  • Diarrhea
  • Vomiting
  • Stomatitis (Inflammation of the mouth)
  • Nausea
  • Constipation
  • Low blood platelets
  • Decreased white blood cell count (neutrophils)
  • Upper respiratory tract infection


Take this medicine in the dose and duration as advised by your doctor. Ibrunat Capsule may be taken with or without food, but it is better to take it at a fixed time.


Ibrunat Capsule is a Bruton’s tyrosine kinase inhibitor. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Fact Box

Chemical Class: Diphenylethers Derivative
Habit Forming: No
Therapeutic Class: ANTI NEOPLASTICS
Action Class: Bruton’s tyrosine kinase (BTK) inhibitors

Quick tips

  • Take it at the same time every day, either with or without food.
  • It is advisable to stay hydrated and drink plenty of fluids while taking this medication.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor your liver function and blood cell count in your blood


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